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Beilstein J. Nanotechnol. 2016, 7, 364–373, doi:10.3762/bjnano.7.33
Figure 1: Nanosensors for in vitro protease detection. For each protease, a highly selective oligopeptide is ...
Figure 2: Mechanistic scheme of the “light switch effect” upon proteolytic cleavage: the fluorophore is switc...
Figure 3: TEM (1a,1b) and HRTEM (1c) images of Fe/Fe3O4-core/shell nanoparticles that are forming the inorgan...
Figure 4: Matrix effects for MMP7, MMP13, and cathepsin L after 60 min of incubation at 25 °C under standard ...
Figure 5: Matrix effects for MMP1, MMP 2, MMP 3, and cathepsin B after 60 min of incubation at 25 °C under st...
Figure 6: Cross-sensitivities of the nanoplatforms used in this study. Further explanations are provided abov...
Figure 7: Bar graph (left, showing means and standard deviations) and box plot (right, indicating the observe...
Figure 8: Calculated p-values; comparison of breast cancer patients and healthy human subjects for all invest...
Figure 9: Average protease activity as a function of breast cancer stage/healthy control group for all nine p...
Beilstein J. Nanotechnol. 2012, 3, 444–455, doi:10.3762/bjnano.3.51
Scheme 1: Preparation of core/shell Fe/Fe3O4 magnetic nanoparticles (MNPs).
Scheme 2: Functionalization of SN38.
Figure 1: TEM of the core/shell Fe/Fe3O4 nanoparticles: (a) freshly synthesized MNPs; (b) MNP-SN38; (c) HRTEM...
Figure 2: Powder XRD patterns of MNP-SN38.
Figure 3: Fluorescence spectra of MNP-SN38 and free SN38 released from MNP.
Figure 4: Toxicity of MNP-SN38 on double stable Mo/Ma after 24 h of loading; the MTT assay was performed for ...
Figure 5: Double-stable Mo/Ma loaded with MNP-SN38 320 g/mL(medium). a: Prussian blue staining and counter st...
Figure 6: Flow cytometry of MNP-SN38 loaded double-stable Mo/Ma after 24 h. Side scatter was used to measure ...
Figure 7: Iron concentration per double-stable Mo/Ma cell loaded with different concentrations of MNP-SN38.
Scheme 3: RAW264.7 cell (monocyte/macrophage) delivered thermochemotherapy.